logo

Treatment Resistant Depression

Treatment Resistant Depression services offered in Bel Air, Perry Hall and Silver Spring, MD

Treatment-resistant depression affects about 30% of people with major depressive disorder. At American Psychiatric Care, based in Bel Air, Silver Spring, and Perry Hall, Maryland, the experienced psychiatrists and psychiatric nurse practitioners care for people struggling with treatment-resistant depression. Schedule an in-person or virtual mental health evaluation with the team by calling the office or using the online booking feature today. 

Treatment Resistant Depression Q&A


What is treatment-resistant depression?

Treatment-resistant depression is a form of depression (ongoing or severe sadness) that hasn’t responded to at least two different antidepressants. That means your symptoms haven’t resolved with these medications.

Treatment-resistant depression is common, but it can become debilitating when not addressed. See the experts at American Psychiatric Care if you’re still feeling depressed after a first-line treatment has failed. 

What are the symptoms of treatment-resistant depression?

Examples of treatment-resistant depression symptoms may include:

  • Long-lasting depressive episodes
  • Severe depression symptoms (sadness)
  • Sleep changes
  • Appetite or weight changes
  • Feeling helpless, hopeless, and/or worthless
  • Anxiety
  • Fatigue
  • Stress
  • Loss of interest in favorite things
  • Social withdrawal
  • Aches and pains
  • Thoughts of suicide

The good news is that you don’t have to live with treatment-resistant depression because relief is within reach at American Psychiatric Care.

What may increase the risk of treatment-resistant depression?

Risk factors for treatment-resistant depression might include:

  • Brain chemistry
  • Family history of treatment-resistant depression
  • Ongoing stress
  • Past trauma
  • Heart, thyroid, cerebrovascular, or autoimmune diseases

However, anyone can develop this form of depression, and the exact cause isn’t fully understood. 

How is treatment-resistant depression diagnosed?

The specialists at American Psychiatric Care diagnose treatment-resistant depression and similar mental health conditions by completing a comprehensive psychiatric evaluation using DSM-5 criteria. They may discuss your:

  • Symptoms
  • Medical history
  • Medications
  • Moods
  • Thoughts
  • Emotions
  • Lifestyle habits 

American Psychiatric Care also offers cognitive testing and genetic testing, which help determine which medications will likely work best to ease your symptoms. Your provider asks about previous depression treatments and your preferences.

How is treatment-resistant depression treated?

Your personalized plan for treatment-resistant depression may consist of:

  • Healthy lifestyle changes
  • Stress management
  • Medication management
  • Spravato® 
  • Psychotherapy
  • Transcranial magnetic stimulation (TMS)

It’s helpful to stay active, eat nutritious foods, and get plenty of sleep. Consider relaxation activities to ease stress or anxiety and maintain a strong social support network. Avoid alcohol, smoking, and drug use. 

American Psychiatric Care can also help you manage any coexisting conditions, such as attention-deficit/hyperactivity disorder (ADHD), schizophrenia, substance use disorder (SUD), mood disorders, and/or dementia.

Schedule a treatment-resistant depression evaluation at American Psychiatric Care by calling the office or booking an in-person or telehealth appointment online today.